Endurance
Exploring the inherent and adaptive components of exercise capacity
Physical exercise is great for our health. So much so that low exercise capacity is in itself a predictor of premature mortality. However, not everybody gets the same benefits from exercise, and some of us have to work much harder to get there. In this study, we try to understand why and identify genes associated with inherent exercise capacity and response to endurance training.
How muscle uses kynurenine clearance to optimize energy production
One man’s trash is another man’s treasure. In this study we identify a recycling mechanism by which muscle helps the body to get rid of a neurotoxic molecule (kynurenine) while using it to support energy production. This mechanism is induced by endurance exercise training and allows muscle cells to extract more energy from sugar, which enhances endurance exercise performance.