Synapses

This study was developed in close collaboration with the laboratory of Dr. Ana Teixeira(MBB, KI). We wanted to understand how changes that occur inside the muscle fibers (when we exercise or in situations of muscle disease) are communicated to the neurons that bring information from the brain and that allow us to move (motor neurons). We identified a molecule called Neurturin, that is released from muscle and encourages motor neurons to stay connected to muscle. This finding could have implications in diseases such as ALS